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Froelich, Christopher
One or more keywords matched the following items that are connected to Froelich, Christopher
Item TypeName
Concept Cell Membrane Permeability
Concept Cell Membrane
Academic Article An antimicrobial activity of cytolytic T cells mediated by granulysin.
Academic Article Perforin-dependent nuclear entry of granzyme B precedes apoptosis, and is not a consequence of nuclear membrane dysfunction.
Academic Article Cytotoxic cell granule-mediated apoptosis: perforin delivers granzyme B-serglycin complexes into target cells without plasma membrane pore formation.
Academic Article Cell death-associated translocation of plasma membrane components induced by CTL.
Academic Article Flow cytometry cannot assess surface binding of perforin to target cells.
Academic Article A clathrin/dynamin- and mannose-6-phosphate receptor-independent pathway for granzyme B-induced cell death.
Academic Article Detection of functional cell surface perforin by flow cytometry.
Academic Article Perforin activity at membranes leads to invaginations and vesicle formation.
Academic Article Modulation of the tumor cell phenotype by IFN-gamma results in resistance of uveal melanoma cells to granule-mediated lysis by cytotoxic lymphocytes.
Academic Article A novel mechanism for protein delivery: granzyme B undergoes electrostatic exchange from serglycin to target cells.
Academic Article Human perforin permeabilizing activity, but not binding to lipid membranes, is affected by pH.
Academic Article Perforin rapidly induces plasma membrane phospholipid flip-flop.
Academic Article Human perforin employs different avenues to damage membranes.
Academic Article Effects of MACPF/CDC proteins on lipid membranes.
Academic Article Membrane pore formation at protein-lipid interfaces.
Academic Article Perforin oligomers form arcs in cellular membranes: a locus for intracellular delivery of granzymes.
Grant Molecular Mechanism of Granule-mediated Apoptosis
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  • Cell Membrane